Invariant natural killer T cells in lupus patients promote IgG and IgG autoantibody production
نویسندگان
چکیده
منابع مشابه
Invariant natural killer T cells in lupus patients promote IgG and IgG autoantibody production.
IgG autoantibodies, including antibodies to double-stranded DNA (dsDNA), are pathogenic in systemic lupus erythematosus (SLE), but the mechanisms controlling their production are not understood. To assess the role of invariant natural killer T (iNKT) cells in this process, we studied 44 lupus patients. We took advantage of the propensity of PBMCs from patients with active disease to spontaneous...
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ژورنال
عنوان ژورنال: European Journal of Immunology
سال: 2014
ISSN: 0014-2980
DOI: 10.1002/eji.201444760